Basic Informations

C.V

Fatma Hanafy Sayed khalil

Department of Animal and Poultry Behavior and Management

Faculty of Veterinary Medicine

Beni Suef University

CURRICULUM VITA

PERSONAL DETAILS

NAME: Fatma Hanafy Sayed khalil

DATE OF BIRTH: December 23, 1977

PLACE OF BIRTH: Emirates

SEX: Female                                                                               NATIONALITY: Egyptian

MARITAL STATUS: Married

ADDRESS in EGYPT: Department of Animal and Poultry Behavior and Management, Beni -Suef University, Beni -Suef, Egypt

TELEPHONE / FAX: 092-642-2906

 MOBILE: 0803940 0444

E-MAIL: fatmahs77@yahoo.com

SCIENTIFIC DEGREES

- Bachelor of Vet. Med. Sci. (2000; Faculty of Veterinary Medicine, Cairo University, Beni –Suef branch, Egypt.

- Master of Sci. in behavior (2005; thesis title: Influence of environmental stressors on response and behavior of Albino rats- Faculty of Veterinary Medicine, Cairo University, Beni –Suef branch, Egypt.

PROFESSIONAL EMPLOYMENT

20001-2005: Animal and Poultry Behavior and Management, Beni Suef University, Beni -Suef, Egypt (teaching the practical courses to undergraduate students)

2005-2009: Assistant Lecturer in Animal and Poultry Behavior and Management, Beni Suef University, Beni -Suef, Egypt

TEACHING EXPERIENCE

-Teaching the practical courses of Animal and Poultry Behavior and Management, Beni Suef University, Beni -Suef, Egypt

Practice of teaching assistance in Kyushu University Japan.

COMPUTER SKILLS

- Knowledge and ability to use most of windows software applications including Microsoft Offices preparation. Screen presentations using PowerPoint in addition to statistical analysis using different computer statistical programs.

- International Computer Driving License (ICDL)

LANGUAGE SKILLS

- Institutional Toefl (517)

- Fair speaking of Japanese language

Good speaking of Arabic language

RESEARCH INTERESTS

Fish , poultry and animal behavior

Academic Records on Kyushu University Japan

Teaching Practice

Presentation Skill for academic meeting

Research training on animal and Marine Bioresource Sciences

Advanced topics on Animal and Marine bioresources

Tutorial on Animal and Marine bioresources

Publications

Original Articles

 

Khalil F, Kang Ik, Undap S, Tasmin R, Qui X, Shimasaki Y, Oshima Y(2013) Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure. Chem 92,125-130.

Nassef M, Matsumoto S, Seki M, Khalil F, Kang IJ, Shimasaki Y, Honjo T (2010) Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes). Chemosphere 80:9, 1095-1100.

Tasmin R.,  Shimasaki Y.,  Tsuyama M., Qiu X., Khali F., Okino N., Yamada N., Fukuda S., Kang IK., Oshima Y. Elevated water temperature reduces the acute toxicity of the widely used herbicide diuron to a green alga, Pseudokirchneriella subcapitata. Environ Sci Pollut Res 2013

Elevated water temperature reduces the acute toxicity of the widely used herbicide diuron to a green alga, Pseudokirchneriella subcapitata R Tasmin, Y Shimasaki, M Tsuyama, X Qiu, F Khalil, N Okino, N Yamada, ... Environmental Science and Pollution Research 21 (2), 1064-1070	18	2014
Accumulation of organotins in wharf roach (Ligia exotica Roux) and its ability to serve as a biomonitoring species for coastal pollution SL Undap, S Matsunaga, M Honda, T Sekiguchi, N Suzuki, F Khalil, X Qiu, ... Ecotoxicology and environmental safety 96, 75-79	8	2013
Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times F Khalil, X Qiu, IJ Kang, I Abo-Ghanema, Y Shimasaki, Y Oshima Ecotoxicology and environmental safety 145, 78-82	2	2017
Effect of ginger and its nanoparticles on growth performance, cognition capability, immunity and prevention of motile Aeromonas septicaemia in Cyprinus carpio fingerlings FMMKF Khalil2 Aquaculture Nutrition	1	2017
Effects of water temperature and light intensity on the acute toxicity of herbicide thiobencarb to a green alga, Raphidocelis subcapitata R Tasmin, Y Shimasaki, M Tsuyama, X Qiu, F Khalil, K Mukai, ... Environmental Science and Pollution Research 25 (25), 25363-25370		2018
Effects of Probiotic on Comfort and Body Care Behaviors of Broilers Reared at Different Stocking Densities RR Ibrahim, F Khalil, AS Mostafa, HH Emeash Journal of Advanced Veterinary Research 8 (3), 60-65		2018
EVALUATION OF MORINGA OLEIFERA LEAVES AND THEIR AQUEOUS EXTRACT IN IMPROVING GROWTH, IMMUNITY AND MITIGATING EFFECT OF STRESS ON COMMON CARP (Cyprinus Carpio) FINGERLINGS F KhalIl, FMM KornI Turkish Journal of Aquatic Sciences 32 (3), 170-178		2017
Stressful effect of repeated subcutaneous injection of tulathromycin on social and grooming behaviors of rats NMAA Fatma Khalil* Asian Journal of Animal and Veterinary Advances		2016
A study on behavior of Japanese medaka (Oryzias latipes) as a biomarker to organophosphorus pesticides exposure FHS Khalil ????

 

Conferences

Fatma Khalil1Sublethal effect of chlorpyrifos on social behavior and brain acetylcholinestrase activity of Japanese medaka (Oryzias latipes). In Society of Environmental Toxicology and Chemistry, September 24-27 -2011 in Kumamoto, Japan.

Fatma Khalil1, Ik-Joon Kang2,Suzanne Undap1, Rumana Tasmin1, Xuchun Qiu1, Yohei Shimasaki1, and Yuji Oshima. Alternations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure.In Society of Environmental Toxicology and Chemistry Asia Pacific Annual Meeting (SETAC AP 2012), to be held during September 24-27, 2012, in Kumamoto, Japan.

Master Title

Influence of some environmental stressors on response and behaviour of laboratory rats

Master Abstract

Abstract Three experiments were conducted on the Department of Hygiene, Management and Zoonoses. Faculty of Veterinary Medicine, Beni-Suef Branch, Cairo University; these experiments were carried out during the period from 15th June 2003 till the day 21 of March 2004. The first experiment was to verify the effect of acute stressors ( repeated handling and immobilization ) on the behaviour and response of virgin female rats, the second was to detect the effect of the same stressors on the response and behaviour of parturient female rats and the third was to investigate the effect of seasonal variation on the response and behavior of adult rats. it was found that these stressors induced some behavioural changes in addition to increase cortisol level and neutrophil / lymphocyte ratio of virgins while the cortisol level of parturient females are not affected and in contrast, the adult rats showed normal or lower cortisol level in response to seasonal variation

PHD Title

A study on behavior of Japanese medaka (Oryzias latipes) as a biomarker to organophosphorus pesticides exposure

PHD Abstract

Summary Agrochemicals, especially pesticides, play an important role in the high productivity achieved in agriculture through the control of pests. However, the release of these substances into the environment has serious environmental consequences The results of this study indicated that OPs (namely chlorpyrifos (CPF) and dichlorvos (DDVP)) may pose risks to Japanese medaka (O. latipes) that are mediated by serious behavioral (swimming, feeding and social) and biochemical alterations (AChE). Accordingly, behavior may serve as a useful biomarker for prediction of the effects of OPs on fish at the population level. As reported in chapter 2, CPF 96 h LC50 was found to be 0.12 mg L-1 and hypoactivity was observed. In the acute exposure test, fish showed hypoactivity relative to the control, with exposure to 0.018, 0.055, and 0.166 mg L–1 inducing swimming speeds that were 55.6%, 39.0%, and 27.3% of those of the control. Moreover, brain acetylcholinesterase activity and swimming speed were significantly correlated. In addition, in the feeding behavior test, CPF 96 h LC50 (0.12 mg L-1) stopped medaka feeding after 24 and 48 h of exposure, with inhibited swimming speed and brain AChE activity occurring after 48 h of exposure. These results suggest that hypoactivity may be used as a sensitive biomarker to acute exposure of fish to CPF. As reported in chapter 3.1, increased swimming speed and schooling duration and decreased solitarity were observed in medaka exposed to sublethal levels of chlorpyrifos (Table.5.1). Sublethal exposure to 0.012 mg L–1 chlorpyrifos (10% of LC50) for 8 d resulted in fish hyperactivity, whereas acetylcholinesterase activity was decreased to 68% of that of the control. In addition, fish exhibited significant alterations in social behavior (schooling duration increased and solitary duration decreased). Taken together, these findings indicated that hyperactivity and increased schooling duration may be sensitive biomarkers to sublethal CPF contamination (Table.5.1) The data presented in Chapter 3.2 confirmed the results reported in chapter 2 and 3.1. Medaka became hypoactive and social behavior (schooling and shoaling) was decreased after 4 d of acute exposure to 0.12 mg L-1. Conversely, fish exhibited hyperactivity and increased schooling duration after 8 d of sublethal exposure to 0.012 mg L-1 followed by normal activity, and decreased schooling duration on day 12. Thus, using a single behavioral response as a biomarker of OPs contamination may be not accurate. Indeed, complex behavioral response is likely the best tool for studying the effect of contaminants as well as their mechanism of action. In addition, behavioral and biochemical alterations in response to CPF exposure were concentration and time dependent. The condition of recording may influence the behavioral response to OPs. In chapter 2 and 3.1, 0.018 mg L-1 and 0.012 mg L-1 were found to be sublethal concentrations to medaka, respectively; however, they induced different behavioral alterations: namely, hypoactivity (0.018 mg L-1 on day 4) and hyperactivity (0.012 mg L-1 on day 8). These different responses might have been due to different conditions of exposure, recording or measurement of swimming speed in the two experiments. The swimming speed of individual fish was recorded in the acute test, whereas in the subacute test swimming speed was measured in a group setting (six fish). Swimming in a group may enhance swimming activity. In chapter 4, 24 h DDVP LC50 was recorded to be 26.2 mg L-1. In addition, sublethal exposure to DDVP at 5 mg L-1 decreased schooling and solitary frequency, as well as swimming speed (hypoactivity). The observed behavioral alterations of medaka in response to OPs exposure suggest that behavior may be used as a sensitive biomarker for prediction of the ecological risk of OPs to the natural ecosystem. Alterations in swimming, feeding and social behaviors, especially schooling, may retard fish growth and reproduction as well as threaten fish survivability at the population level. AChE inhibition may also be used as an early warning of OPs contamination. AChE assay is quicker and easier than behavioral based measurements. However, correlation between behavioral and biochemical endpoint is essential to understanding and interpretation of behavioral response to OPs. In chapter 3.2, sublethal exposure to CPF (0.012 mg L-1) for 8 days (inhibition of AChE activity to 64.3% of control) was found to cause hyperactivity. However, 0.12 mg L-1 (inhibition of AChE activity to 37.3% of the control) resulted in hypoactivity. These results may be attributed to the action of anticholinesterase agents that can evoke hyperactivity with low levels of AChE impairment and hypoactivity as impairment increases. In conclusion, the reported behavioral alterations in this study reveal that behavior is a useful biomarker for assessment and prediction of the ecological risk OPs pose to the natural ecosystem. Moreover, AChE activity might be an early warning of OPs contamination.