olfat shehata magouda farg allah

assistant lecturer in clinical pathology

Basic Informations

C.V


Olfat Shehata Mogoda

Email address:olfar_shehata@yahoo.com

Mobile no.:    01152295507

Work phone:  +20822322066

Fax no.:+2 082 2327982

Master Title

Comparative clinicopathological studies on the effect of different probiotics in broilers

Master Abstract

This study was designed to compare between Bactocell and Revitilyte-PlusTM as probiotics and their effect on the general performance, hematological parameters, biochemical constituents of blood and immune response of broilers. Three hundred one day old broiler chicks were included in this study which were divided equally into six groups (each 50 chicks) as follow: group (C) fed on a balanced ration and considered as the control group, group (L) fed on a balanced ration with probiotic (1) supplementation (Revitilyte-PlusTM at a rate of 1 g/4 liter of water). group (P) fed on a balanced ration with probiotic (2) supplementation (Bactocell, at a rate of 1kg/ton ration), group (C+S) fed on a balanced ration and in the 5th week of age was infected with 8 x 1012 Salmonella kentucky for 2 successive days (1ml in the first day and 0.5 ml in the second day) , group (L+S) fed on a balanced ration with probiotic (1) supplementation (Revitilyte-PlusTM at a rate of 1 gm/4 liter of water) and in the 5th week of age was infected with 8 x 1012 Salmonella kentucky for 2 successive days (1ml in the first day and 0.5 ml in the second day), group (P+S) fed on a balanced ration with probiotic (2) supplementation (Bactocell, at a rate of 1kg/ton ration) and in the 5th week of age was infected with 8 x 1012 Salmonella kentucky for 2 successive days (1ml in the first day and 0.5 ml in the second day). The period of experiment extended to7 weeks through which weighing of birds and collection of samples was done. Results revealed that Bactocell is better than Revitilyte-PlusTM as a probiotic as it increased the body weight , improved the FCR , provided more immunoglobulins and lower mortalities than Revitilyte-PlusTM.

PHD Title

Clinicopathological studies on the hepatoprotective potential of spirulina aglae against various hepatopathies experimentally induced in rats.

PHD Abstract

This study was designed to investigate the effect of Spirulina on Cc14-induced liver toxicity in rats. This was performed through evaluation of hematological parameters, biochemical constituents of blood and immune response of rats. Female Wistar albino rats were divided into 4 equal groups. Group (C), where rats were fed on a balanced ration and kept as control. Group (SP), where rats received daily Spirulina by oral gavage (500 mg/kg b.wt) for 10 weeks. Rats in group (Ccl4) were given 4% Ccl4 S/C (0.2ml/100g b.wt) 3 times/ week for 10 weeks. Group SP+ Ccl4, where rats received Spirulina and Ccl4 as the same previously mentioned doses for 10 weeks. Our data revealed that Spirulina intake resulted in significant decrease in the elevated liver enzymes (ALT, AST and AP), significant increase in the measured antioxidant enzymes (GSH, catalase and SOD), decrease in MDA and TNF-a and prolongation of prothrombin time. In addition, the lipid profile of SP+ Ccl4 group showed significant decrease in cholesterol, triglycerides and LDL and significant increase in HDL. Electrophoretic pattern of serum proteins showed significant increase in gamma globulins and decrease in alpha globulins. We concluded that, Spirulina has protective effect against hepatotoxicity induced by Ccl4 in rats.

All rights reserved ©olfat shehata magouda farg allah