Pulmonary and pleural toxicity of potassium octatitanate fibers, rutile titanium dioxide nanoparticles, and MWCNT-7 in male Fischer 344 rats

Research Abstract

In conclusion, there is clear evidence that POT fibers are toxic in the lung and pleura of male rats. POT fibers were biopersistent in the lung and mesothelium of rats, provoking inflammation and tissue and DNA damage. These results are in agreement with the physical characteristics of these fibers and the potential adverse health effects of thin, long, biopersistent fibers. The pulmonary and pleural toxicity of POT fibers was similar or greater than that of MWCNT-7, a known carcinogen to the rat lung

Research Keywords

MWCNT-7, a known carcinogen